The first place finish for Cole, who is married to the Chelsea footballer Ashley Cole, is the first for a British contender in three years of the magazine’s poll.
A surprise result at number four was the American singer Britney Spears, who was expected to fall out of the top 100 following a turbulent year.
FHM’s 100 Sexiest supplement, featuring 52 pages of “the hottest women in the world”, is in the June edition of FHM, on sale now.
Celebritysnap.com top 10:
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1. Jessica Alba (3)
2. Megan Fox (2)
3. Adriana Lima (6)
4. Freida Pinto (10)
5. Britney Spears (4)
6. Elisha Cuthbert (7)
7. Cheryl Cole (1)
8. Kristin Kreuk (8)
9. Keeley Hazell (5)
10. Anna Friel (9)